7 Best Running Shoes for Compartment Syndrome 2021

The best running shoes for compartment syndrome will give you a range of options to choose from managing CECS when running. Best Running Shoes for Compartment Syndrome

Compartment Syndrome (CECS) is a dramatic rise in the lower leg pressure caused by forefoot running. Try the best running shoes for compartment syndrome. 

This results in chronic pain in the lower section of the leg when running with compartment syndrome.

Reviews: 7 Best Running Shoes for Compartment Syndrome 2021

1. Merrell Men’s Vapor Glove 2 Trail Running Shoe with Breathable mesh

This is one of the top picks in the minimalist shoe category which is guaranteed to improve your performance while cautioning you against compartment syndrome related injuries.

Best Running Shoes for Compartment Syndrome View on Amazon

This footwear has a solid footwear feature to treat compartment syndrome.

Its footbed and outsole are integrated into a single unit making this a minimalist choice that offers you barefoot riding experience. This footwear features a thin outsole which provides a distinct feel when running in the track while protecting you from injury.

With this zero-drop feature and ground feel sensitivity, the Merrell Vapor Glove 2 is the ideal pick for managing compartment syndrome and improving your running form.

At 5.5mm, this unit’s rubber outsole is highly flexible, durable, and capable of molding to the curves of your underfoot. This footwear offers you a glove-like fit to meet the functional and mechanical needs of your foot as you run along.

The upper section is made of lightweight washable and breathable wire mesh feature which is comfortable to wear in hot conditions. The upper section conforms to the shape of the runner’s feet and facilitates the natural movement of the foot even for protracted periods.


  • Excellent arch support
  • Offers ground feel sensitivity
  • Good traction for improved balance
  • Flexible and breathable feature


  • Small toe box and narrow frame

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2. Vivobarefoot Women’s Stealth 2 Walk Shoe 100% Fabric and Synthetic

The upper section of the Stealth 2 is made of durable and durable V-Wed HEX mesh which features support and stretch features for improved foot control and adaptability.

Vivobarefoot Women's Stealth 2 Walk Shoe 100% Fabric and Synthetic View on Amazon

This unit’s upper section is designed to improve ventilation with each stride. The inner part is made using Outlast temperature regulating material for improved comfort and enhanced performance even compartment syndrome runners.

This feature is reinforced by an EVA cage for improved structural support and flexibility that allows the construction material to maintain its shape.

The outsole of this footwear offers you balanced traction which is made possible by the V Road Engineering technology. The under sole is specially designed for treadmill and track performance. It features wet and dry slip resistance grip features providing excellent motion control while allowing your heel to engage with the running surface. The Vivobarefoot’s outsole is made of puncture-resistant material which serves to protect the midfoot area from injury.

The barefoot inspired nature of this footwear is evidenced by the absence of a midsole, arch support, and heel extension. This serves to stimulate the user’s feet in a natural way by leaving them more susceptible to injury and under development.


  • Perfect for everyday running and walking
  • Balanced traction capability
  • Offers upper lightweight support


  • Lacks arch support

3. Sockwa X8- Breathable, Barefoot/Minimal Shoe Odor Free

This is the go-to shoe if you are looking for improved mechanical effectiveness to improve your balance and reinforce your feet and ankles.

Sockwa X8- Breathable, Barefoot/Minimal Shoe Odor Free View on Amazon

If you are dealing with chronic exertional compartment syndrome, this Sockwa model will cushion your knees from high impact with its ground feel themed outsole.

This barefoot minimalist footwear is specially designed to offer you a rich sensory feeling and an injury-free running experience. The breathable feature of this shoe wear is one of its best-selling points.

Its fabric is made with a combination of the odor-free and moisture-absorbent lining which makes up its stylish and durable exterior. The Ariaprene breathable fabric features moisture-wicking capabilities and anti-odor features for those hot summer days.

This shoe’s forefoot is snug and made of flexible fabric that wraps around your foot. Its lightweight nature makes it less confiding that a pair of socks.

It leaves enough room for normal toe function while the rubber under sole offers more you unlimited flexibility.

The flexible nature of this unit allows it to be rolled up your foot. What’s more? The Sockwa X8 takes the memory of your foot which serves to eliminate stiffness.


  • Unique moisture wicking future
  • Offers a secure fit
  • Lightweight in design


  • Small toe box

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4. Vibram Men’s KSO EVO CrossTraining Shoe Lightly Padded Tongue

This is one of Vibram brand’s thinner, soft and light editions of minimalist running shoes. This shoe’s structure is designed to complement the foot’s design by wrapping each individual toe to its fabric.

Vibram Men's KSO EVO CrossTraining Shoe Lightly Padded Tongue View on Amazon

This shoe’s remarkable construction design not only improves the user’s safety and comfort but also keeps your performance natural and lightweight.

This footwear is built on a ground platform that offers the best responsiveness and maximum articulation.

This outsole of this shoe measures 3mm thick featuring the V-soul design which is made using the Vibram TS Trek material. The tread design of this unit provides excellent traction on all types of surfaces.

This shoe features a lightweight and flexible sole design which gives your feet the freedom to move more flexibly. The outer sole is both tough and durable with a zero drop capability for that improved natural footing.

The upper section of this shoe wear features an adjustable lace-up system that distinguishes from the previous slip-on design. The breathable mesh design of this unit is reinforced by a PU film and a 2mm EVA insole.


  • Highly affordable
  • Offers a dynamic ground feel
  • Excellent traction
  • Highly durable
  • Lightweight
  • The breathable and flexible upper section


  • Tight feeling around the toes

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5. ASICS Men’s Gel-Venture 6 Running Shoe Rearfoot GEL Cushioning

For compartment syndrome prone runners, this presents the ideal choice by offering you unrestricted fit for increased functionality.

ASICS Men's Gel-Venture 6 Running Shoe Rearfoot GEL Cushioning View on Amazon

This shoe enhances the natural stride by pushing your forefoot strike in the desired direction during running by utilizing the low-to-ground platform and reduced heel to toe gradient features.

The under sole section generates the feeling of a perfect minimalist running shoe. This feature offers you excellent ground feedback and allows your foot to stay in the line while protecting it from harm. For improved traction, the under sole section features multi-flex indentation.

The minimalist-inspired design means that this footwear offers you unrestricted fit and allows your feet to function with maximum freedom.

Thanks to the low-to-the-ground orientation, this footwear enhances your natural stride. The lightweight design of this shoe will leave you feeling weightless for enhanced running performance.

The upper section of this footwear is made of light and soft material which is capable of bending around the contours of your foot during your run. Whereas the upper part is not very breathable, this is the perfect fit during low temperatures.


  • Highly flexible
  • Inexpensive
  • Offers a ground-feel sensitivity
  • Lightweight design


  • Not suitable for wearing in hot weather

6. Vivo Barefoot Primus Lite Running Trainer Shoe Textile & Synthetic

This Vivobarefoot shoe wear is specially designed for maximum freedom owing to its minimalist design.

Vivo Barefoot Primus Lite Running Trainer Shoe Textile & Synthetic View on Amazon

Less shoe cover offers you the least possible interference with your natural runs which leaves you in total control for all run and work out activities. This vegan-friendly barefoot exercise shoe allows you to experience maximum movement as you work out.

The outsole of this unit seeks to achieve a delicate balance in achieving its status as a minimalist shoe. The outsole is thin enough to avoid accumulating heat and provide flexibility.

This dramatic shift in design translates into less leg protection. Further, the highly advanced PRO5 material that makes up this part offers sufficient traction to run on flat and hard surfaces.

The upper section of the shoe is made of a lightweight and breathable material. This is achieved through the use of a thin fabric whereas a mesh material covers the ventilated areas.

On the lateral side of the shoe, is a pocket mesh that provides sufficient airflow and a barefoot sensation. As a result, the shoe wear provides a subtle design that provides a barefoot sensation.


  • Highly stable
  • Zero drop design for improved forefoot strike
  • Extraordinary flexibility
  • Highly responsive
  • Stylish


  • Minimal heel and arch support

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7. Xero Shoes Prio Minimalist Barefoot Trail and Road Running Shoe

This iconic shoe brand is just what you need to achieve improved awareness of the body movement. This model also features a wider toe box, zero drops, and a fully adjustable strap for an improved fit.

Xero Shoes Prio Minimalist Barefoot Trail and Road Running Shoe View on Amazon

The Xerox Prio series offers you a combination of superior protection and freedom. If you are dealing with Chronic Exertional Compartment Syndrome, this shoe is the right pick whether you are going on a run or hitting the treadmill in the gym.

The under the sole of the Prio features 5mm of FeelTrue rubber offering you enough protection and much-needed ground response. A 2mm insole lining eliminates the option of a barefoot sensation depending on your current emotion.

At only 7.6 oz, you will barely notice you have these shoes on. For a more secure feeling, this shoe wear features a reflective heel and instep straps which hold on to your feet securely.

Its construction design features 100% vegan-friendly materials. These shoes are guaranteed to offer you superior performance and life-changing comfort by allowing you to use your feet naturally. Like all Xero shoes, this model also features a 5000-mile sole warranty.


  • Lightweight in design
  • Secure fit
  • Guaranteed natural feel and motion


  • Relatively expensive

Consideration in Best Running Shoes for Compartment Syndrome

1. Flexibility

Minimalist shoes are preferred for managing compartment syndrome due to their high flexibility which allows the user to pursue a natural motion throughout the heel-to-toe transition.

The ideal running shoes should provide a combination of flexibility and support.

2. Heel-to-toe drop

Minimalist footwear has a varying range of heel-to-toe drops measuring 0-6 mm.

If you are just getting acquainted with minimalist running, higher drops are preferred to allow you to get used to ground contact.

The right heel to toe drop distance will be determined by your level of experience in using minimalist shoes.

3. Weight and Versatility

The lightweight frame of minimalist shoes makes them ideal for speed workouts and racing. These shoes utilize fewer technologies which ensure that you do not drag down on the racing track.

This feature also allows you to improve your speed record eventually. This model can be used in both track runs and mixed trails.

These shoes can also be used in speed workouts, performance training, and sportswear. The ideal pick should be versatile enough for all terrains and weather conditions.

4. Responsiveness and Stability

The best performing minimalist shoes should be capable of providing a light platform and low heel to drop capability.

In addition, comfort and responsiveness are important features for improved performance on the field.

In addition to shock absorption capabilities, the ideal shoe should be highly stable for runners dealing with compartment syndrome.

5. Breathable feature

The upper section of the shoe wear should be comfortable enough to allow the user to run comfortably in hot weather conditions.

In addition, it should be flexible enough to allow for improved foot control and adaptability.

6. The lacing system and Traction

You might want to go for shoe wear with an innovative lacing system for improved control. The absence of an efficient lacing system can cause blisters and loss of control during descent and ascent.

The ideal pick of barefoot running should offer maximum traction in both urban and rugged running tracks.

7. Durability

The minimalist range of running shoes is designed to reduce pain and tiredness which renders them to be relatively pricey.

Hence, it is imperative to invest in a durable pair with enhanced ruggedness in the upper and outsole sections.

The most durable options feature a combination of natural and textile materials in the upper section.


One of the most prevalent challenges faced by runners with compartment syndrome is heel strike landing which increases pressure in the lower leg dramatically.

You need a minimalist shoe to give your feet that natural feel given their zero-drop heel feature and barefoot sensation.

The Sockwa X-8 breathable minimalist shoe go-to shoe if you are looking for improved mechanical effectiveness.

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